"Statistically based experimental designs have been available for over a century. However, many preclinical researchers are completely unaware of these methods, and the success of experiments is usually equated only…
Variation is present in every experiment. Learn about DoE techniques to control variation, and to maximise data quality. This workshop presents classical techniques to design efficient experiments as well as the tools to analyze their results. The principles of sample size calculations, strategies to remove undesirable sources of variability like the use of blocks and controls, as well as the most commonly used experimental designs are discussed. The statistical analysis of designed experiments is progressively introduced, starting with the t-test method used to compare two groups. Then, the analysis of variance technique (ANOVA) is extensively covered from simple one-factor experiments to more advanced multi-factor situations where the interaction between factors needs to be considered. Multiple comparisons techniques used to locate differences are also presented.
Learn about advanced experimental designs to account for experimental various types of constraints such as time, available resources, material heterogeneity, randomization restrictions when certain factors are more difficult or costly to change than others, different sizes of experimental units as well as repeated measures. In this course, the construction of advanced designs and their statistical analysis is covered with the help of real case studies.